Cpaptm1b(EUCOMM)Wtsi
Targeted Allele Detail
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| Symbol: |
Cpaptm1b(EUCOMM)Wtsi |
| Name: |
centrosome assembly and centriole elongation protein; targeted mutation 1b, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:5609805 |
| Gene: |
Cpap Location: Chr14:56764218-56812882 bp, - strand Genetic Position: Chr14, 28.28 cM
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| Alliance: |
Cpaptm1b(EUCOMM)Wtsi page
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| IMPC: |
Cpap gene page |
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| Mutant Cell Line: |
EPD0028_7_G05 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:208632
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| Parent Cell Line: |
JM8.N4 (ES Cell)
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| Strain of Origin: |
C57BL/6N
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| Project Collection: |
EUCOMM
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_gt1
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Mutation details: The L1L2_gt1 cassette was inserted at position 56792283 of Chromosome 14 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 56793168. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp mediated recombination. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:173534)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Cpap Mutation: |
44 strains or lines available
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| Original: |
J:208632 Bazzi H, et al., Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1491-500 |
| All: |
2 reference(s) |
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Analysis Tools
